[1] Taylor, D.L. and Wang, Y.-L. (1978) Molecular cytochemistry: incorporation of fluorescently labeled actin into living cells. Proc. Natl. Acad. Sci. USA 75:857-861.

[2] Wang, Y.-L. and Taylor, D.L. (1979) Distribution of fluorescently labeled actin in living sea urchin eggs during early development. J. Cell Biol. 82:672-679.

[3] Wang, Y.-L. and Taylor, D.L. (1980) Preparation and characterization of a new molecular cytochemical probe: 5-iodoacetamidofluorescein-labeled actin. J. Histochem. Cytochem. 28:1198-1206.

[4] Taylor, D.L. and Wang, Y.-L. (1980) Fluorescently labeled molecules as probes of the structure and function of living cells. Nature 284:405-410.

[5] Wang, Y.-L. and Taylor, D.L. (1981) Probing the dynamic equilibrium of actin polymerization by fluorescence energy transfer. Cell 27:429-436.

[6] Wang, Y.-L. and Taylor, D.L. (1981) Exchange of 1,N6-etheno-ATP with actin-bound nucleotides as a tool for following the steady-state exchange of subunits in F-actin solutions. Proc. Natl. Acad. Sci. USA 78:5503-5507.

[7] Wang, Y.-L., Lanni, F., McNeil, P.L., Ware, B.R. and Taylor, D.L. (1982) Mobility of cytoplasmic and membrane associated actin in living cells. Proc. Natl. Acad. Sci. USA 79:4660-4664.

[8] Wang, Y.-L., Heiple, J.M. and Taylor, D.L. (1982) Fluorescent analog cytochemistry of contractile proteins. Methods Cell Biol. 24:1-11.

[9] Wang, Y.-L., Bonder, E.M., Mooseker, M.S. and Taylor, D.L. (1983) Effects of the intestinal microvillar 95k-dalton protein (villin) on the polymerization and subunit exchange of actin. Cell Motility 3:151-165.

[10] Wang, Y.-L.(1984) Reorganization of actin filament bundles in living fibroblasts. J. Cell Biol. 99:1478-1485.

[11] McKenna, N.M., Meigs, J.B. and Wang, Y.-L. (1985) Identical distribution of fluorescently labeled brain and muscle actins in living cardiac fibroblasts and myocytes. J. Cell Biol. 100:292-296.

[12] Wang, Y.-L. (1985) Exchange of actin subunits at the leading edge of living fibroblasts: possible roles in treadmilling. J. Cell Biol. 101:597-602.

[13] McKenna, N.M., Meigs, J.B. and Wang, Y.-L.(1985) Exchangeability of alpha-actinin in living cardiac myocytes and fibroblasts. J. Cell Biol. 101:2223-2232.

[14] Meigs, J.B. and Wang, Y.-L. (1986) Reorganization of alpha-actinin and vinculin induced by a phorbol ester in living cells. J. Cell Biol. 102:1430-1438.

[15] Wang, Y.-L. (1986) Redistribution of alpha-actinin and vinculin in living cells following ATP depletion and replenishment. Exp. Cell Res. 167:16-28.

[16] McKenna, N.M. and Wang, Y.-L. (1986) Possible translocation of alpha-actinin and actin along stress fibers. Exp. Cell Res. 167:95-105.

[17] McKenna, N.M. Johnson, C.S. and Wang, Y.-L. (1986) Formation and alignment of Z-lines in living chick myotubes microinjected with rhodamine-labeled alpha-actinin. J. Cell Biol. 103:2163-2171.

[18] Stickel, S.K. and Wang, Y.-L. (1987) Alpha-actinin containing aggregates in transformed cells are dynamic structures. J. Cell Biol. 104:1521-1526.

[19] Wang, Y.-L. and Goren, M.B. (1987) Sequential and differential delivery of lysosomal fluorescent probes into phagosomes in mouse peritoneal macrophages. J. Cell Biol. 104:1749-1754.

[20] Wang, Y.-L. (1987) Mobility of filamentous actin in living cytoplasm. J. Cell Biol. 105:2811-2816.

[21] Stickel, S.K. and Wang, Y.-L. (1988) Synthetic peptide GRGDS induces dissociation of alpha-actinin and vinculin from the sites of focal contacts. J. Cell Biol. 107:1231-1239.

[22] Johnson, C.S., McKenna, N.M. and Wang, Y.-L. (1988) Association of microinjected myosin and its subfragments with myofibrils in living muscle cells. J. Cell Biol. 107:2213-2221.

[23] McKenna, N.M., Johnson, C.S., Konkel, M.E. and Wang, Y.-L. (1988) Organization of myosin in living muscle and non-muscle cells. in Cellular and Molecular Biology of Muscle Development, (L. Kedes and F. Stockdale, eds.) Alan R. Liss, New York, pp.237-246.

[24] McKenna, N.M., Wang, Y.-L. and Konkel M.E. (1989) Formation and movement of myosin-containing structures in living fibroblasts. J. Cell Biol. 109:1163-1172.

[25] Wang, Y.-L. (1989) Fluorescent analogue cytochemistry: tracing functional protein components in living cells. Methods Cell Biol. 29:1-12.

[26] McKenna, N.M. and Wang, Y.-L. (1989) Culturing cells on the microscope stage. Methods Cell Biol. 29:195-205.

[27] Sanders, M.C. and Wang, Y.-L. (1990) Exogenous nucleation sites fail to induce detectable polymerization of actin in living NRK cells. J. Cell Biol. 110:359-365.

[28] Cao, L.-G. and Wang, Y.-L. (1990) Mechanism of the formation of contractile ring in dividing cultured animal cells. I. Recruitment of preexisting actin filaments into the cleavage furrow. J. Cell Biol. 110:1089-1095.

[29] Cao, L.-G. and Wang, Y.-L. (1990) Mechanism of the formation of contractile ring in dividing cultured animal cells. II. Cortical movement of actin filaments into the cleavage furrow. J. Cell Biol. 111:1905-1911.

[30] Wang, Y.-L. (1990) Analysis of structural dynamics in living cells with fluorescence video microscopy. in Optical Microscopy for Biology, (B. Herman and K. Jacobson, eds), Wiley-Liss, New York, pp.449-458.

[31] Wang, Y.-L. and Sanders, M.C. (1990) Analysis of cytoskeletal structures by the microinjection of fluorescent probes. in Non-invasive Techniques in Cell Biology (S. Grinstein and J.K. Foskett, eds), Wiley-Liss, New York, pp.177-212.

[32] Fishkind, D.J., Cao, L.-G. and Wang, Y.-L. (1991) Microinjection of the catalytic fragement of myosin light chain kinase into dividing cells: Effects on mitosis and cytokinesis. J. Cell Biol. 114:967-975.

[33] Wang, J., Cao, L.-G., Wang, Y.-L. and Pederson, T. (1991) Localization of pre-messenger RNA at discrete nuclear sites. Proc. Natl. Acad. Sci. USA, 88:7391-7395.

[34] Sanders, M.C. and Wang, Y.-L. (1991) Assembly of actin cortex occurs at distal ends of growing neurites. J. Cell Sci., 100:771-780.

[35] Wang, Y.-L. (1991) Preparation and characterization of tetramethylrhodamine-labeled myosin. Methods Enzymol. 196:497-505.

[36] Wang, Y.-L. (1991) Dynamics of the cytoskeleton in live cells. Curr. Opinion Cell Biol. 3:27-32.

[37] Cao, L.-G., Babcock, G.G., Rubenstein, P.A. and Wang, Y.-L. (1992) Effects of profilin and profilactin on actin structure and function in living cells. J. Cell Biol. 117:1023-1029.

[38] Sanders, M.C., Goldstein, A.L. and Wang, Y.-L. (1992) Thymosin b4 is a potent regulator of actin polymerization in living cells. Proc. Natl. Acad. Sci. USA 89:4678-4682.

[39] Wang, Y.-L. (1992) Fluorescence microscopic analysis of cytoskeletal organization and dynamics. in Cytoskeleton: A Practical Approach (K. L. Carraway and C.A.C. Carraway, eds), Oxford University Press, Oxford, pp.1-22.

[40] Cao, L.-G., Fishkind, D.J. and Wang, Y.-L. (1993) Localization and dynamics of nonfilamentous actin in cultured cells. J. Cell Biol. 123:173-181.

[41] Fishkind, D.J. and Wang, Y.-L. (1993) Orientation and three-dimensional organization of actin filaments in dividing cultured cells. J. Cell Biol. 123:837-848.

[42] Wang, Y.-L., Silverman, J.D. and Cao, L.-G. (1994) Single particle tracking of surface receptor movement during cell division. J. Cell Biol. 127:963-971.

[43] Wang, Y.-L. (1994) Microinjection of proteins into somatic cells. in Handbook of Cell Biology (J.E. Celis, ed.), Academic Press, San Diego. pp.16-21.

[44] Jacobson, M.R., Cao, L.-G., Wang, Y.-L. and Pederson, T. (1995) Dynamic localization of Rnase MRP RNA in the nucleolus observed by fluorescent RNA cytochemistry in living cells. J. Cell Biol. 131:1649-1658.

[45] Fishkind, D.J. and Wang, Y.-L. (1995) New Horizons for Cytokinesis. Curr. Opinion Cell Biol. 7:23-31.

[46] Cao, L.-G. and Wang, Y.-L. (1996) Signals from the spindle midzone are required for the stimulation of cytokinesis in cultured epithelial cells. Mol. Biol. Cell 7:225-232.

[47] Pelham, R.J. Jr., Lin, J.J.-C. and Wang, Y.-L. (1996) A high-molecular mass non-muscle tropomyosin isoform stimulates retrograde organelle transport. J. Cell Sci. 109:981-989.

[48] Tarachandani, A. and Wang, Y.-L. (1996) Site-directed mutagenesis enabled preparation of a functional fluorescent analog of profilin: biochemical characterization and localization in living cells. Cell Motil. Cytoskeleton 34:313-323.

[49] Fishkind, D.J., Silverman, J.D. and Wang, Y.-L. (1996) Function of spindle microtubules in directing cortical movement and actin filament organization in dividing cultured cells. J. Cell Sci. 109:2041-2051.

[50] Anderson, K.I., Wang, Y.-L. and Small, J.V. (1996) Coordination of protrusion and translocation of the keratocyte involves rolling of the cell body. J. Cell Biol. 134:1209-1218.

[51] Wheatley, S.P. and Wang, Y.-L. (1996) Midzone microtubule bundles are continuously required for cytokinesis in cultured epithelial cells. J. Cell Biol. 135:981-989.

[52] Jacobson, M.R., Cao, L.-G., Taneja, K., Singer, R.H., Wang, Y.-L. and Pederson, T. (1997) RNase P: Nucleolar association of the RNA subunit. J. Cell Sci. 110:829-837.

[53] Wheatley, S.P., Hinchcliffe, E.H., Glotzer, M., Hyman, A., Sluder, G. and Wang, Y.-L. (1997) CDK1 inactivation regulates anaphase spindle dynamics and cytokinesis in vivo. J. Cell Biol. 138:385-393.

[54] Jacobson, M.R., Pederson, T. and Wang, Y.-L. (1997) Conjugation of fluorescent probes to proteins and nucleic acids. in Handbook of Cell Biology, Vol. IV (J.E. Celis, ed.), Academic Press, San Diego., pp.5-10.

[55] Pelham, R.J. Jr. and Wang, Y.-L. (1997) Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc. Natl. Acad. Sci. USA 94:13661-13665.

[56] Wang, Y.-L. (1998) Digital deconvolution of fluorescence images for biologists. Methods Cell Biol. 56:305-315.

[57] Wheatley, S.P. and Wang,Y.-L. (1998) Fluorescence immunolocalization. Methods Cell Biol. 57:313-332.

[58] Wang, Y.-L. and Pelham, R.J. Jr. (1998) Preparation of a flexible, porous polyacrylamide substrate for mechanical studies of cultured cells. Methods Enzymol. 298:489-496.

[59] Wheatley, S.P., O'Connell, C.B. and Wang, Y.-L. (1998) Inhibition of chromosomal separation provides insights into cleavage furrow stimulation in cultured epithelial cells. Mol. Biol. Cell 9:2173-2184.

[60] O'Connell, C.B., Wheatley, S.P., Ahmed, S. and Wang Y.-L. (1999) The small GTP-binding protein Rho regulates cortical activities in cultured cells during division. J. Cell Biol. 144:305-313.

[61] Dembo, M. and Wang, Y.-L. (1999) Stresses at the cell-to-substrate interface during locomotion of fibroblasts. Biophys. J. 76:2307-2316.

[62] Pelham, R.J. Jr. and Wang Y.-L. (1999) High resolution detection of mechanical forces exerted by locomoting fibroblasts on the substrate. Mol. Biol. Cell 10:935-945.

[63] O'Connell, C.B. and Wang, Y.-L. (2000) Mammalian spindle orientation and position respond to changes in cell shape in a dynein-dependent fashion. Mol. Biol. Cell 11:1765-1774.

[64] Lo, C.-M., Wang, H.-B., Dembo, M. and Wang, Y.-L. (2000) Cell movement is guided by the rigidity of the substrates. Biophys. J. 79:144-152.

[65] Kaverina, I., Krylyshkina, O., Gimona, M., Beningo, K., Wang, Y.-L. and Small, J.V. (2000) Enforced polarization and locomotion of fibroblasts lacking microtubules. Curr. Biol. 10:739-742.

[66] Wang, H.-B., Dembo, M. and Wang, Y.-L. (2000) Substrate flexibility regulates growth and apoptosis of normal but not transformed cells. Am. J. Physiol. 279:C1345-C1350.

[67] Faulkner, N.E., Dujardin, D.L., Tai, C.Y., Vaughan, K.T., O'Connell, C.B., Wang Y.-L. and Vallee, R.B. (2000) A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function. Nature Cell Biol. 2:784-791.

[68] Munevar, S., Dembo, M. and Wang, Y.-L. (2001) Traction force microscopy of normal and transformed fibroblasts. Biophys. J. 80:1744-1757.

[69] O'Connell, C.B., Warner, A.K. and Wang, Y.-L. (2001) Distinct roles of the equatorial and polar cortices in the cleavage of adherent cells. Curr. Biol. 11:702-707.

[70] Beningo, K.A., Dembo, M., Kaverina, I., Small, J.V. and Wang, Y.-L. (2001) Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts. J. Cell Biol. 153:881-887.

[71] Wang, H.-B., Dembo, M., Hanks, S.K. and Wang, Y.-L. (2001) Focal adhesion kinase is involved in mechanosensing during fibroblast migration. Proc. Natl. Acad. Sci. USA 98:11295-11300.

[72] Munevar, S., Wang, Y.-L. and Dembo, M. (2001) Distinct roles of frontal and rear cell-substrate adhesions in fibroblast migration. Mol. Biol. Cell.12:3947-3954.

[73] Wang, Y.-L. (2001) The mechanism of cytokinesis: reconsideration and reconciliation. Cell Struct. Funct. 26:633-638.

[74] Beningo, K.A. and Wang, Y.-L. (2002) Flexible substrata for the detection of traction forces. Trends Cell Biol. 12:79-84.

[75] Beningo, K.A. and Wang, Y.-L. (2002) Fc-receptor mediated phagocytosis is regulated by mechanical properties of the target. J. Cell Sci. 115:849-856.

[76] Kaverina, I., Krylyshkina, O., Beningo, K., Anderson, K., Wang, Y.-L. and Small, J.V. (2002) Tensile stress stimulates microtubule outgrowth in living cells. J. Cell Sci. 115:2283-2291.

[77] Murata-Hori, M., Tatsuka, M. and Wang, Y.-L. (2002) Probing the dynamics and functions of Aurara B kinase in living cells during mitosis and cytokinesis. Mol. Biol. Cell 13:1099-1108.

[78] Murata-Hori, M. and Wang, Y.-L. (2002) The kinase activity of aurora B is required for kinetochore-microtubule interactions, bi-directional chromosomal movements, and spindle microtubule organization during mitosis. Curr. Biol. 12:894-899.

[79] Murata-Hori, M. and Wang, Y.-L. (2002) Both midzone and astral microtubules are involved in the delivery of cytokinesis signals to the equatorial cortex: insights from the mobility of Aurora B. J. Cell Biol. 159:45-53.

[80] Harrington, K.S., Javed A., Drissi, H., McNeil, S., Lian, J.B., Stein, J.S., van Wijnen, A.J., Wang, Y.-L. and Stein G.S. (2002) Transcription factors RUNX1/AML1 and RUNX2/Cbfa1 dynamically associate with stationary subnuclear domains. J. Cell Sci. 115:4167-4176.

[81] Beningo, K.A., Lo, C.-M. and Wang, Y.-L. (2002) Flexible polyacrylamide substrata for the analysis of mechanical interactions at cell-substratum adhesions. Methods Cell Biol. 69:325-339.

[82] Marganski, W.A., Dembo, M. and Wang, Y.-L. (2002) Measurements of cell-generated deformations on flexible substrata using correlation-based optical flow. Methods Enzymol. 361:197-211.

[83] Kaverina, I., Krylyshkina, O., Beningo, K.A., Anderson, K., Wang, Y.-L. and Small, J.V. (2002) Tensile stress stimulates microtubule outgrowth in living cells. J. Cell Sci. 115:2283-2291.

[84] Wang, Y.-L.(2003) Computational restoration of fluorescence images: noise reduction, deconvolution, and pattern recognition. Methods Cell Biol. 72:337-348.

[85] Munevar, S, Wang, Y.-L. and Dembo, M. (2004) Regulation of mechanical interactions between fibroblasts and the substrate by stretch-activated calcium entry. J. Cell Sci. 117:85-92.

[86] Lo, C.-M., Buxton, D.B., Chua G.C., Dembo, M., Adelstein, R.S. and Wang, Y.-L. (2004) Nonmuscle myosin IIB is involved in the guidance of fibroblast migration. Mol. Biol. Cell 15:982-989.

[87] Wang, Y.-L., Burridge, K., Dembo, M., Gabbiani, G., Hanks, S.K., Hosoya, H., Janmey, P., Karlsson, R., Lindberg, U., Mabuchi, I., Otey, C., Rottner, K., Small, J.V., Wang, C.-L.A. and Zigmond, S.(2004) Biomedical Research Publication System. Science 303:1974-1976.

[88] Beningo, K.A., Dembo, M. and Wang, Y.-L. (2004) Responses of fibroblasts to anchorage of dorsal extracellular matrix receptors. Proc. Natl. Acad. Sci. USA 101:18024-18029.

[89] Shiu, Y.T., Marganski, W.A., Usami, S., Schwartz, M.A., Wang, Y.-L., Dembo, M. and Chien, S. (2004) Rho mediates shear-enhancement of endothelial cell migration and traction force generation. Biophys. J. 86:2558-2565.

[90] Murata-Hori, M., Sluder, G. and Wang, Y.-L. (2005) Regulation of cell cycle by the anaphase spindle midzone. BMC Cell Biol. 5:49.

[91] Guha, M., Zhou, M. and Wang, Y.-L. (2005) Cortical actin turnover during cytokinesis requires myosin II. Curr. Biol. 15:732-736.

[92] Wang, Y.-L. (2005) The mechanism of cortical ingression during early cytokinesis: thinking beyond the contractile ring hypothesis. Trends Cell Biol. 15:581-588.

[93] Discher, D., Janmey, P. and Wang, Y.-L. (2006) Tissue cells feel and respond to the stiffness of their substrates. Science 310:1139-1143.

[94] Warner, A.K., Keen, J.H. and Wang, Y.-L. (2006) Dynamics of membrane clathrin-coated structures during cytokinesis. Traffic 7:205-215.

[95] Guo, W.H., Frey, M.T., Burnham N.A. and Wang, Y.-L. (2006) Substrate rigidity regulates the formation and maintenance of tissues. Biophys. J. 90:2213-2220.

[96] Frey, M.T., Tsai, I.Y., Russell, T.P., Hanks, S.K. and Wang, Y.-L. (2006) Cellular responses to 3D substrate topography: role of myosin II and focal adhesion kinase. Biophys. J. 90:3774-3782.

[97] Beningo, K.A., Hamao, K., Dembo, M., Wang, Y.-L. and Hosoya, H. (2006) Traction forces of fibroblasts are regulated by the Rho-dependent kinase but not by the myosin light chain kinase. Arch. Biochem. Biophys. 456:224-231.

[98] Wang, Y.-L. (2006) Introduction to fluorescence imaging of live cells - an annotated checklist. in Cell Biology, A Laboratory Handbook, 3rd Edition, Vol III (J.E. Celis, ed.), Academic Press, San Diego. pp.107-110.

[99] Wang, Y.-L., Hahn, K.L., Murphy, R.F. and Horwitz, A.F. (2006) From imaging to understanding: Frontiers in live cell imaging. Bethesda, MD April 19-21, 2006. J. Cell Biol. 174:481-484.

[100] Mader, C.C., Hinchcliffe, E.H. and Wang, Y.-L. (2007) Probing cell shape regulation with patterned substratum: requirement of myosin II-mediated contractility. Soft Matter 3:357-363.

[101] Beningo, K.A. and Wang, Y.-L. (2007) Double-hydrogel substrates as a model system for 3D cell culture. in Adhesion Protein Protols, 2nd Edition (A.S. Coutts, ed.), Humana Press, Totowa. pp.203-211.

[102] Wang, Y.-L. (2007) Flux at focal adhesions: slippage clutch, mechanical gauge, or signal depot. Science STKE 377:pe 10.

[103] Frey, M.T, Engler, A., Discher, D.E., Lee, J., and Wang, Y.-L. (2007) Microscopic methods for measuring the elasticity of gel substrates for cell culture: microspheres, microindenters, and atomic force microscopy. Methods Cell Biol. 83:48-63.


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