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| Dynamics of Amorphous Actin Structures in Motile Cells |
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| L.-g. Cao, D.J. Fishkind and Y.-l. Wang (1993) |
| J. Cell Biol. 123:173-181. |
| Besides filament bundles and filaments in lamellipodia, there are also a number of amorphous actin aggregates with unknown functions in cultured cells. These structures can be detected easily in cells microinjected with fluorescently labeled actin. |
| Rearward Movement of Amorphous Actin Nuggets |
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Size = 260 x 232 pixels.| Many, but not all, of these actin aggregates move rearward, with a speed and pattern similar to those found for the "cortical flow". New aggregates appear continuously behind the lamellipodia. |
| Actin Aggregates Associated with Membrane Vesicles |
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Size = 316 x 192 pixels.| Actin aggregates are associated with the "macropinosomes" that form at lamellipodia and move toward the cell center. These macropinosome may move in a way similar to the movement of Listeria and other intracellular parasitic micro-organisms. |