Dynamic Adhesion Structures in Transformed Cells
S.K. Stickel and Y.-l Wang (1987)
J. Cell Biol. 104:1521-1526.
Cells interact physically with their environment through adhesion structures. To study adhesion structures in transformed cells, Normal Rat Kidney cells transformed with Rous Sarcoma virus were microinjected with fluorescently labeled alpha-actinin, which incorporates into cellular adhesion structures.


Rapid Changes and Movements of Amorphous Adhesion Structures in Transformed NRK Cells
Size = 320 x 240 pixels.
Recording Time = 3 minutes.
High Resolution = 540K Bytes.
Low Resolution = 355K Bytes.



Size = 320 x 240 pixels.
Recording Time = 3 minutes.
High Resolution = 936K Bytes.
Low Resolution = 369K Bytes.

These timelapse sequences show flower-lik, rapidly changing adhesion structures located on the bottom surface of the cell like feet. These structures are likely involved in the invasive behavior of transformed cells.


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